Historisk sett har medisin mot depresjon vært kontroversielt. I begynnelsen var trisykliske antidepressiva og MAOI de eneste tilgjengelige alternativene, Adult males de hadde begrensede fordeler og mange bivirkninger. Atypiske antidepressiver: Antidepressive midler med forskjellige virkningsmekanismer som ikke hører hjemme i disse tre gruppene

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